Fluoxymesterone is an extremely powerful anabolic androgenic steroid that was first released in the late 1950’s by Upjohn under the trade name Halotestin. Shortly after, Ciba Pharmaceuticals would release the hormone under the Ultandren name, but Halotestin has remained the most recognizable brand name. Pharmacia, formerly Upjohn, now manufactures the Halotestin brand name.
When Halotestin first hit the market, it was touted as holding numerous therapeutic benefits. This extremely potent anabolic steroid was prescribed for the treatment of muscle wasting, androgen deficiency in men, lean tissue repair, malnutrition, and for healing bone fractures. It would also be regularly used to treat prolonged exposure to cortisone, paraplegia, breast cancer and often given to burn victims. Unlike many anabolic steroids, Halotestin was regularly prescribed to men and women, and while its modern day use is somewhat limited it is still used to treat breast cancer in some women. The hormone is still used to treat androgen deficiencies in some men, but it’s rare and is approved for osteoporosis treatment in some postmenopausal women.
In the world of performance enhancement, Halotestin holds a reputation of being one of the most powerful and fast acting steroids on the market. However, it’s not one a lot of steroid users will use. This steroid will not build a lot of mass despite a massive anabolic rating; in fact, it really won’t do much at all for mass promotion. This is a steroid that is generally known as a raw strength steroid, but Halotestin is also found in some cutting cycles. It’s not too uncommon for some bodybuilders to supplement with Halotestin the last few weeks before a competition. It can produce some nice conditioning effects, as well as really aid in pushing through the end of a brutal diet. However, the side effects of this steroid are no joking matter, they can be pretty harsh, and that will keep most people away.
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Halotestin Function & Traits:
Fluoxymesterone is a testosterone derived anabolic androgenic steroid or more specifically a structurally altered form of Methyltestosterone. Halotestin is the testosterone hormone with an added methyl group at the 17th carbon position to allow oral ingestion. It also possesses an added fluoro group at carbon 9 and 3 and a hydroxyl group at carbon 11. These modifications inhibit the steroid’s aromatization and greatly increase its androgenic nature. The androgenic nature and activity of Halotestin will be far beyond Methyltestosterone.
By its structural design, Halotestin carries an anabolic rating of 1,900 and an androgenic rating of 850. All ratings are measured against pure testosterone, which carries a rating of 100 in both categories. This means Halo as it’s often known carries ratings that are almost beyond reason, but its anabolic rating is tremendously deceiving. While it carries a massive anabolic rating, its anabolic translation in human beings appears to be near zero. This steroid simply doesn’t translate into any notable anabolic effect and will primarily function by androgenic activity.
Halotestin carries with it some tremendously powerful effects, some of the most powerful revolving around red blood cells. Halo has he ability to greatly increase hematocrit and hemoglobin levels as well as red blood cell mass. It also appears to act through cells that are already committed to erythropoietin response. These effects are largely responsible for the strength effects promoted, as well as the increased level of energy the steroid can provide.
Halotestin also carries with it strong fat loss effects. Halo has the ability to promote the regulation of fatty acid oxidation in the liver, as well as fast-twitch muscle mitochondria. Through these taits as well as the red blood cell interaction, we have a steroid that can have a pronounced effect on visual conditioning aspects in an individual who is already fairly lean.
Effects of Halotestin:
The effects of Halotestin, while tremendously powerful do not represent what we’d label a truly versatile anabolic steroid. This steroid carries very specific points of use, and while it can be beneficial the potential side effects will make it unnecessary for most men. The primary effects of Halotestin revolve around strength and aggression. The issue of aggression and anabolic steroids is often blown out of proportion, but in the case of Halo it truly can enhance an aggressive nature. This in turn can cause the athlete to push harder and be even stronger. While it can enhance aggression there are some important things to keep in mind. Halotestin cannot alter your personality, take away your ability to distinguish between right and wrong or alter your decision making process. It can give the individual a stronger, aggressive nature, but what one does with aggression determines if it’s right or wrong. Aggression in of itself is not a bad thing, it can be a very positive tool; what we do with aggression determines if it’s right or wrong. For the individual who is naturally violent and angry, the use of Halotestin will make him a more aggressive jerk. For the sane individual, he’ll have more aggression to put in the gym or in a competition.
Due to the strength and aggression promotion, this makes Halotestin a popular steroid among power lifter, strength athletes and fighters shortly before competition. A few weeks of use leading up to competition is very common, and the boost in strength can potentially be greater than any other anabolic steroid could provide. This same strength and aggression can also be useful to the competitive bodybuilder a few weeks out from his show. Competitive bodybuilding dieting is brutal and perhaps the hardest way to diet on earth. Towards the end most become extremely drained and have a very difficult time pushing through their training. Adding in Halotestin those last few weeks can help push them through this extremely difficult time. It will also provide the individual with a much harder and more defined look; however, there’s an important note. While Halo can greatly improve visually related conditioning, you must be extremely lean, contest bodybuilding lean to really get anything out of it. Most steroid users will never see this level of leanness and there will be no beneficial purpose of use to them.
This largely sums up the effects of Halotestin regarding beneficial effects. The steroid is not a mass building steroid, and it’s not one that’s used as a foundational steroid in any cycle. This is a short-term use steroid that carries specific benefits for specific purposes. In a therapeutic setting, while it is approved for some points of treatment, it has become exceedingly rare.
Side Effects of Halotestin:
Halotestin is not a devastating steroid when it comes to potential adverse effects, there are far worse compounds. However, it’s not a compound we can call extremely user friendly, especially when we consider its hepatotoxicity and potential effects on cardiovascular health. For this reason, most will need to stay away from the compound. It is possible to use Halotestin without problems, but it will take some effort and largely doesn’t warrant use based on its limited purposes of use. In order to understand the side effects of Halotestin and all you can do to afford protection, we have broken them down into their separate categories along with all you need to know.
[1] Estrogenic:
Although a testosterone derived anabolic steroid, Halotestin does not aromatize and will not produce estrogenic related side effects. Water retention and gynecomastia are impossible with this steroid. The concurrent use of an anti-estrogen with Halotestin will present no benefit. An anti-estrogen may be needed depending on the other compounds in the cycle, but it is not necessary due to Halotestin use.
[2] Androgenic:
Halo is an extraordinarily androgenic steroid, and as a result, the side effects of Halotestin can surround a strong androgenic nature. This can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. While such effects are strongly dependent on individual response and genetic predispositions, the androgenic power of Halo greatly increases the odds. This power is so great, some studies have suggested that Fluoxymesterone may actually promote phallic enlargement.
Halotestin is greatly affected by the 5-alpha reductase enzyme, the same enzyme responsible for the reduction of testosterone to dihydrotestosterone. For this reason, the use of a 5-alpha reductase inhibitor such as Finasteride may reduce the related androgenic side effects of Halotestin. Such use will not completely subdue this steroid’s androgenic activity, but it could potentially reduce it. However, those who are strongly susceptible to androgenic side effects will probably need to forgo this steroid’s use.
Due to its extreme androgenic nature, the side effects of Halotestin can be extreme in women promoting strong virilization symptoms. Virilization symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. The effects are so strong the odds of avoiding virilization will be impossible for most women. The only time Halo could be recommended for female use is in the treatment of androgen sensitive inoperable breast cancer. This steroid has no place in performance enhancing cycles of female athletes.
[3] Cardiovascular:
Halotestin can have a strong, negative impact on cardiovascular health, especially regarding cholesterol management. This can include significant increases in LDL cholesterol and significant suppression of HDL cholesterol. This is largely due to its hepatic nature revolving around its resistance to the liver. Halotestin may also lead to high blood pressure and negatively affect triglyceride levels. Such issues in a long-term capacity could lead to left ventricle hypertrophy. Due to the negative cardiovascular effects of Halo, long-term exposure could increase the risk of cardiovascular disease.
If Halotestin is to be used, it is imperative that the individual does not suffer from high cholesterol or blood pressure. If the individual is healthy enough for use, it is further imperative he does all he can to promote the continuation of healthy levels and keep a close eye on them. Management should include an extremely healthy lifestyle, a diet rich in omega fatty acids and one that is overall cholesterol friendly. The overall diet should also be limited in simple sugars and saturated fats, and should be conjoined with regular cardiovascular activity. Many will also find supplementing with antioxidant supplements that promote healthy cholesterol levels to be very valuable.
[4] Testosterone:
The side effects of Halotestin include natural testosterone suppression, and it will be extreme. However, the reason for suppression is a bit of a mystery with this steroid due to an inconsistent suppression of gonadotropins. Despite this fact, it will suppress natural testosterone production significantly, making the inclusion of exogenous testosterone necessary for most men. Those who do not include exogenous testosterone therapy will fall into a low testosterone condition. This will occur regardless of genetic superiority and can come with a host of bothersome symptoms. Regardless of the severity of symptoms, low testosterone is an extremely unhealthy state. Those who include exogenous testosterone will avoid this low level outcome. The form of testosterone you choose is inconsequential. All that matters is that you provide your body with what it needs.
Once the use of Halotestin comes to an end and all exogenous steroidal hormones have cleared the system, natural testosterone production will begin again. Natural recovery assumes no prior low level condition. It further assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) due to improper steroid use. While production will begin on its own, levels will not return to normal for several months. For this reason, the implementation of a Post Cycle Therapy (PCT) program is often recommended. This will greatly stimulate natural testosterone production, and ensure you have adequate amounts of testosterone for proper bodily function. It will not return you to normal on its own, this will still take several months, but it will speed up the process and ensure a much smoother recovery.
[5] Hepatotoxicity:
Halotestin is a C17-alpha alkylated (C17-aa) anabolic steroid, which refers to the structural change at the 17th carbon position. Specifically, this refers to the added methyl group at the 17th carbon position that protects the hormone through oral ingestion. While necessary to the hormone’s survival, unfortunately it causes it to carry a toxic nature. Of all oral C17-aa anabolic steroids, Halotestin carries one of the strongest hepatotoxic natures of all. Liver enzyme values will increase with the use of this steroid, and more than likely substantially. Increased liver enzyme values does not equate to damage but is an indicator of stress and can be a strong indicator of damage to come.
If Halotestin is to be used, the liver must be healthy to begin with. Further, the individual must make an effort to reduce and limit the total amount of stress to the liver. In order to limit stress, Halo should not be used for more than 4 weeks, with many finding 2 weeks of use to be all that’s needed, such as the 2 weeks leading up to competition. The individual should also incorporate the use of a liver detoxifier supplement when using this steroid; in fact, it should not be used without such a protectant. All who use Halotestin are further encouraged to avoid excess alcohol consumption due to the tremendous stress this causes the liver. Avoiding all alcohol consumption will be the safest path to follow. The final note on stress reduction is limiting the use of over the counter (OTC) medications. Many OTC medications are very hepatotoxic, and in some cases, more so than many anabolic steroids. The use of OTC medications should be limited to when only absolutely necessary.
Halotestin Administration:
For the purpose of performance enhancement, Halotestin doses can range from 10-40mg per day. 10mg per day will produce noticeable results, but most will find 20mg per day to be a more beneficial dose that is controllable with proper use by a healthy adult male. If such a dose is tolerated well and more is wanted later on, 40mg per day can be attempted. However, such a dose will greatly enhance the probability of negative effects and may be overkill for some men. Regardless of the dose, 2-4 weeks of use is all that can be recommended. Further, regardless of the dose, like most oral anabolic steroids Halo should be taken on an empty stomach. Taking it with food may decrease its bioavailability.
Halotestin can also be taken to treat androgen issues and is normally given at a dose of 20mg per day. This dose is normally adjusted downward after short-term initial therapy has past. The total dose will normally rest in the 5-20mg per day range based on the individual’s needs. Such use can at times be long-term; however, a very sharp and constant eye on cardiovascular and liver health will be implemented. Such treatment is somewhat rare in the modern age, but can be beneficial for some men.
Availability of Halotestin:
Halotestin is not abundantly available like many anabolic steroids. Steroids like single ester testosterones, Dianabol, Trenbolone and Nandrolone compounds largely dominate the market with a relatively low demand for Halo. Human grade Halotestin can be hard to find on the black market, and very few underground labs carry it. While the supply of this steroid is rather low, it can still be found with a little digging. As a bonus, due to the lower demand of this steroid it is not counterfeited nearly as often as many of the more popular anabolic steroids. This is good news, if you find it more than likely it will be real. Large internet based suppliers will normally be your best bet, but even then most will not carry it. Gym dealers will be a long shot.
Buying Halotestin Online – Warning:
Buying Halotestin online is the only way most men will be able to purchase this steroid unless it is prescribed for androgen insufficiency, which is rare. While this is the best way for a purchase and counterfeits are very rare, it still comes with a massive legal risk. If you live in the U.S. and you buy Halotestin online you will be breaking the law. Halotestin, like all anabolic steroids is classified as a Schedule III controlled substance by way of the Steroid Control Act of 1990, later reinforced by the Steroid Control Act of 2004. Many countries carry similar strict laws, although the U.S. is about as strict as it gets. However, some countries will be far more lenient when it comes to anabolic steroid legislation, especially in Eastern Europe, Asia and South America. Regardless, online purchasing is commonly frowned upon in most countries regardless of the actual steroid classification of the country in question.
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Halotestin Reviews:
Halotestin is one of the most powerful anabolic steroids to ever exist. Despite its power it only holds a few beneficial traits for most individuals, making it a poor choice for the majority of performance enhancing athletes. The average gym rat will not find this to be a steroid he wants to include in his cycle. There’s no strategic advantage, and the risks far outweigh the reward. The average gym rat can easily reach his goals with the use of other compounds. Of course, some gym rats are tempted to try it, a rapid and dramatic increase in strength can sound appealing, but it’s important to remember the harsh nature of this steroid.
For the competitive athlete or bodybuilder, Halotestin can have a place. However, for the bodybuilder other steroids can provide the same level of conditioning without the added stress to the body. At the same time, no other steroid can add the aggression and push that’s sometimes needed to finish a brutal contest diet. If it’s needed, proceed with caution. For the strength athlete, the power lifter or fighter, this steroid can be more beneficial for this individual perhaps more so than anyone else. However, once again he must supplement cautiously and remember the potential long-term effects.
Halotestin Profile:
[9-alpha-fluoro-11-beta-hydroxy-17-alpha-methyl-4-androstene-3-one,17b-ol]
Molecular Weight: 336.4457
Formula: C20 H29 F O3
Melting Point: 240C
Manufacturer: Pharmacia-Upjohn
Effective Dose: 10-40mgs/day
Active life: 6-8 hours
Detection Time: 2 months
Anabolic/Androgenic ratio:1,900/850
Halotestin References:
Treatment with anabolic steroids increases the activity of the mitochondrial outer carnitine palmitoyltransferase in rat liver and fast-twitch muscle. Biochem Pharmacol. 1991 Mar 1;41(5):833-5.
Effects of synthetic androgen fluoxymesterone on triglyceride secretion rates in the rat.Proc Soc Exp Biol Med. 1975 Jun;149(2):452-4.
Metabolism of anabolic steroids in humans: synthesis of 6 beta-hydroxy metabolites of 4-chloro-1,2-dehydro-17 alpha-methyltestosterone, fluoxymesterone, and metandienone. Steroids. 1995 Apr;60(4):353-66.
Influence of fluoxymesterone on in vitro erythropoiesis affected by leukemic cells.Exp Hematol. 1984 Mar;12(3):171-6.
[Erythropoietin in serum and urine in healthy persons and patients with chronic renal disease upon hypoxic stimulation and hypoxic stimulation after pretreatment with fluoxymesterone (authors transl)]
Fluoxymesterone therapy in anemia of patients on maintenance hemodialysis: comparison between patients with kidneys and anephric patients. J Dial. 1977;1(4):357-66
Combination hormonal therapy with tamoxifen plus fluoxymesterone versus tamoxifen alone in postmenopausal women with metastatic breast cancer. An updated analysis.Cancer. 1991 Feb 15;67(4):886-91.
Effect of non aromatizable androgens on LHRH and TRH responses in primary testicular failure.Horm Metab Res. 1984 Sep;16(9):492-7.
The effect of synthetic androgens on the hypothalamic-pituitary-gonadal axis in boys with constitutionally delayed growth. J Pediatr. 1979 Apr;94(4):657-62.
The effect of synthetic androgens on the hypothalamic-pituitary-gonadal axis in boys with constitutionally delayed growth. J Pediatr. 1979 Apr;94(4):657-62.
Steroids and hematopoiesis. II. The effect of steroids on in vitro erythroid colony growth: evidence for different target cells for different classes of steroids. J Cell Physiol. 1976 Jun;88(2):135-43.
Testing for fluoxymesterone (Halotestin) administration to man: identification of urinary metabolites by gas chromatography-mass spectrometry. J Steroid Biochem. 1990 Aug 28;36(6):659-66.
Toxic effects of anabolic-androgenic steroids in primary rat hepatic cell cultures. J Pharmacol Toxicol Methods. 1995 Aug;33(4):187-95.
Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin.Endocrinology. 1984 Jun;114(6):2100-6.
The relationship of androgen to the thyrotropin and prolactin responses to thyrotropin-releasing hormone in hypogonadal and normal men. J Clin Endocrinol Metab. 1981 Feb;52(2):173-6.
| Testosterone | ||
| Name | Abbr | CasNO. |
| Testosterone | TB | 58-22-0 |
| Testosterone Enanthate | TE | 315-37-7 |
| Testosterone Cypionate | TC | 58-20-8 |
| Testosterone Propionate | TP | 57-85-2 |
| Testosterone Phenylpropionate | TPP | 1255-49-8 |
| Testosterone Isocaproate | TI | 15262-86-9 |
| Testosterone Decanoate | TD | 5721-91-5 |
| Testosterone Undecanoate | TU | 5949-44-0 |
| Testosterone Acetate | TA | 1045-69-8 |
| Testosterone Sustanon(Sustanon 250) | S250 | Sustanon 250 |
| Clostebol Acetate（ 4-Chlorotestosterone） | CA | 855-19-6 |
| Methyltestosterone(17-Alpha-Methyl-Testosterone) | MT | 65-04-3 |
| Andropen | ||
| TNT | ||
| T3 (Cytomel, Liothyronine sodiu) | T3 | 55.06.1 |
| T4 (L-Thyroxine ) | T4 | 25416-65-3 |
| 1-Testosterone Cypionate(Dihydroboldenone) | DHB | 65 06 5 |
| Nandrolone | ||
| Name | Abbr | CasNO. |
| Nandrolone Decanoate | ND | 360-70-3/DECA |
| Nandrolone Phenypropionate | NPP | 62-90-8 |
| Trenbolone | ||
| Name | Abbr | CasNO. |
| Trenbolone Base | TRB | 10161-33-8 |
| Trenbolone Hexahydrobenzyl | TBHC | 23454-33-3 |
| Trenbolone Acetate | TBA | 10161-34-9 |
| Trenbolone Enanthate | TBE | 472-61-5 |
| Trenbolone cyclohexylmethylcarbonate | HEX | 23454-33-3 |
| Boldenone | ||
| Name | Abbr | CasNO. |
| Boldenone | B | 846-48-0 |
| Boldenone Undecylenate/EQ | BU | 13103-34-9 |
| Drostanolone Propionate(Masteron p) | DP | 521-12-0 |
| Drostanolone Enanthate (Masteron E) | DE | 472-61-145 |
| Methenolone | ||
| Name | Abbr | CasNO. |
| Methenolone Enanthate (Primobolan E ) | ME | 303-42-4 |
| Methenolone Acetate (Primobolan A ) | MA | 434-05-9 |
| Antiestrogen | ||
| Name | Abbr | CasNO. |
| Tamoxifen Citrate(Nolvadex) | 54965-24-1 | |
| Clomiphene Citrate(Clomid) | 50-41-9 | |
| Exemestane(Aromasin) | 107868-30-4 | |
| Toremifene Citrate(Fareston) | 89778-27-8 | |
| Anastrozole(arimidex) | 120511-73-1 | |
| Letrozole(Femara) | 112809-51-5 | |
| Sex Enhancement | ||
| Name | Abbr | CasNO. |
| Vardenafil（Levitra） | 224785-91-5 | |
| Tadalafil(Cialis) | 171596-29-5 | |
| Yohimbine Hydrochloride | 65-19-0 | |
| Clenbuterol | 37148-27-9 | |
| Viagra(Sildenafil Citrate) | 171599-83-0 | |
| Oral Steroid | ||
| Name | Abbr | CasNO. |
| Methasterone(Superdrol) | SUP | 3381-88-2 |
| Oxymetholone (Anadrol) | OXY | 434-07-1 |
| Oxandrolone (Anavar) | OXA | 53-39-4 |
| Stanozolol (Winstrol) | ST | 10418-03-8 |
| Proviron (Mesterolone) | PRO | 1424-00-6 |
| Oral Turinabol(4-Chlorodehydromethyltestosterone) | 2446-23-3 | |
| Dianabol (Methandrostenolone, methandienone) | DB | 72-63-9 |
| Fluoxymesterone (Halotestin) | FLU | 76-43-7 |
| Cabergoline/Dostinex | 81409-90-7 | |
| Trestolone Acetate（MENT） | 6157-87-5 | |
| Accutane (Isotretinoin) | ISO | 4759-48-2 |
Post time: Feb-13-2023